The need for a new search landscape for excipients with desirable in vivo properties

Key Points

• The goal is to identify excipients that exhibit favorable in vivo properties for better drug formulations.
• Review of current excipients and their limitations
• Assessment of in vivo properties and bioavailability metrics
• Identification of gaps in existing excipient databases
• Current excipients often lack optimal bioavailability and properties
• Emerging excipients show potential for improved therapeutic effectiveness
• Novel screening methods are needed to evaluate excipients' in vivo performance