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May 1, 2025SHILAP Revista de lepidopterología22 citationsOpen Access

Independent prognostic importance of endothelial activation and stress index (EASIX) in critically ill patients with heart failure: modulating role of inflammation

FYFang YinKWKai Wang

Structured PICO

Are elevated log2(EASIX) levels associated with higher 1-year all-cause mortality in ICU patients with heart failure?

P
Population
ICU patients suffering from heart failure
I
Intervention
Elevated log2(EASIX) levels (endothelial activation and stress index)
O
Outcome
1 year all-cause mortalityhard clinical

Elevated EASIX levels serve as an independent prognostic marker for 1-year mortality in critically ill heart failure patients, with effects modulated by baseline inflammation and severity scores.

Abstract

It found an independent association between elevated log2(EASIX) levels and a higher risk of 1 year all-cause mortality in ICU patients suffering from HF, with a stronger effect observed in patients with low levels of APS III or white blood cell counts, or high levels of body mass index or albumin. This association may be partially mediated by blood urea nitrogen and red cell distribution width.

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Cite This Study

Yin et al. (2025) studied this question.

synapsesocial.com/papers/69da20648988aeabbe686851https://doi.org/10.3389/fmed.2025.1560947
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