The inactivation or down-regulation of the mgrB gene was shown to be a source of colistin resistance in K. pneumoniae. Interestingly, identical genetic events were identified among clonally unrelated isolates.

Bookmark

Cite This Study

Poirel et al. (Wed,) studied this question.

synapsesocial.com/papers/69da288cb48bb130d4684685 https://doi.org/https://doi.org/10.1093/jac/dku323

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Multiplex PCR for detection of acquired carbapenemase genes2011 · 1,999 citations
2Molecular Characterization of the PhoP-PhoQ Two-Component System in Escherichia coli K-12: Identification of Extracellular Mg 2+ -Responsive Promoters

The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae | Synapse

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Multiplex PCR for detection of acquired carbapenemase genes2011 · 1,999 citations
2Molecular Characterization of the PhoP-PhoQ Two-Component System in Escherichia coli K-12: Identification of Extracellular Mg 2+ -Responsive Promoters

1999 · 173 citations

3The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay2008 · 102 citations

4Multilocus Sequence Typing of Klebsiella pneumoniae Nosocomial Isolates2005 · 1,359 citations

5Urinary Tract Infections in a South American Population: Dynamic Spread of Class 1 Integrons and Multidrug Resistance by Homologous and Site-Specific Recombination2008 · 60 citations