What question did this study set out to answer?

To assess the ability of sub-Saharan African countries to monitor Mycobacterium tuberculosis genomic changes over 25 years.

April 12, 2026Open Access

Geographical distribution of Mycobacterium tuberculosis complex lineages in sub-Saharan Africa: An interactive review.

Key Points

To assess the ability of sub-Saharan African countries to monitor Mycobacterium tuberculosis genomic changes over 25 years.
Examined genomic data from 49 countries in sub-Saharan Africa
Analyzed a total of 8141 GenBank entries
Included 163 unreported whole genome sequences from a specific institute
Sub-Saharan Africa accounts for 85% of tuberculosis cases in Africa
Diverse lineages of Mycobacterium tuberculosis were identified
Genomic monitoring capabilities vary significantly across countries

Abstract

The capacity of the 49 sub-Saharan African countries, which account for 85% of tuberculosis cases in Africa (WHO, 2025), to monitor the genomic dynamics of Mycobacterium tuberculosis complex strains responsible for the disease was examined for the period 2000-2025.A total of 8141 GenBank entries, supplemented by 163 as yet unreported whole genome sequences prepared at the Institut

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