What question did this study set out to answer?

This research aims to determine the effectiveness of specific biomarkers in identifying brain damage in dogs suffering from neurological distemper.

April 12, 2026Open Access

Evaluation of Selected Brain Damage Biomarkers in the Determination of Brain Damage in Dogs With Neurological Distemper

Key Points

This research aims to determine the effectiveness of specific biomarkers in identifying brain damage in dogs suffering from neurological distemper.
Measure serum concentrations of NSE, GFAP, CK-BB, IgG, and IgM
Compare biomarker levels in dogs with neurological distemper vs. healthy controls
Statistical analysis of biomarker levels to assess significance
Serum levels of NSE, GFAP, and CK-BB were significantly elevated in affected dogs
IgG and IgM levels were also increased but not as significantly as the three biomarkers
Findings support the potential diagnostic role of NSE, GFAP, and CK-BB in brain damage assessment

Abstract

Serum NSE, GFAP, CK-BB, IgG and IgM concentrations were found to be significantly increased in dogs with neurological distemper. The results of this study indicate that NSE, GFAP, and CK-BB biomarkers may have diagnostic significance in determining brain damage.

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Cite This Study

Kapar et al. (Fri,) studied this question.

synapsesocial.com/papers/69db37964fe01fead37c595d https://doi.org/https://doi.org/10.1002/vms3.70894

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