July 29, 2020Open Access

Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes: parallel population-based cohort studies in English and Swedish routine care

Structured PICO

Does continuing ACEI/ARB treatment after an episode of AKI increase the risk of heart failure or subsequent AKI in previous ACEI/ARB users?

P

Population

Previous ACEI/ARB users who had an episode of acute kidney injury (AKI)

I

Intervention

Continued treatment with ACEI/ARB after an episode of AKI

C

Comparator

Stopped ACEI/ARB treatment after an episode of AKI

O

Outcome

Risk of heart failure or subsequent AKIhard clinical

Continuing ACEI/ARB therapy after an episode of acute kidney injury appears safe and does not increase the risk of heart failure or recurrent AKI compared to stopping the medication.

Abstract

Previous ACEI/ARB users who continued treatment after an episode of AKI did not have an increased risk of heart failure or subsequent AKI compared to those who stopped the drugs.

Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes: parallel population-based cohort studies in English and Swedish routine care

Structured PICO

Abstract

Cite This Study

Also Consider

Also Consider