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May 1, 1992Circulation1,056 citationsOpen Access

Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction.

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HIHiroshi ItoTTT TomookaNSNoriko Sakai

Structured PICO

Does lack of myocardial perfusion on MCE immediately after successful thrombolysis predict poor recovery of left ventricular function in anterior myocardial infarction?

P
Population
Patients with anterior acute myocardial infarction (AMI) who had angiographically successful reflow after thrombolysis
I
Intervention
Myocardial contrast echocardiography (MCE) assessment of myocardial perfusion
O
Outcome
Recovery of left ventricular functionsurrogate

Myocardial contrast echocardiography reveals that angiographic reflow does not guarantee tissue-level reperfusion, and residual perfusion defects predict poor LV functional recovery.

Abstract

MCE demonstrates that angiographically successful reflow cannot be used as an indicator of successful myocardial reperfusion in AMI patients. The residual contrast defect in the risk area demonstrated immediately after reflow is a predictor of poor functional recovery of the postischemic myocardium.

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Cite This Study

Ito et al. (1992) studied this question.

synapsesocial.com/papers/69dd66e226032fe00d100f7bhttps://doi.org/10.1161/01.cir.85.5.1699
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