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July 1, 2000Journal of Bacteriology540 citationsOpen Access

Positive Correlation between Virulence of Pseudomonas aeruginosa Mutants in Mice and Insects

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GJGeorg JanderLRLaurence G. RahmeFAFrederick M. Ausubel

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Abstract

Strain PA14, a human clinical isolate of Pseudomonas aeruginosa, is pathogenic in mice and insects (Galleria mellonella). Analysis of 32 different PA14 mutants in these two hosts showed a novel positive correlation in the virulence patterns. Thus, G. mellonella is a good model system for identifying mammalian virulence factors of P. aeruginosa.

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Jander et al. (2000) studied this question.

synapsesocial.com/papers/69dd6829c5e71f7918101078https://doi.org/10.1128/jb.182.13.3843-3845.2000
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