Background the cause may be structural and non-structural, thyroid hormone known to affect reproductive biology. This study was conducted with aim to evaluate the correlation between thyroid disorder and different causes of abnormal uterine bleeding in perimenopause women.Materials transvaginal ultrasound and endometrial biopsy was performed for the patients. Data were analyzed using SPSS software (version 26). P≤ 0.05 was considered statistically significant.Results: The mean age of participants was 44 years old, with 53.1% (26 women) between 40 and 45, 31(63.3%) multiparous, 38(77.6%) euthyroid, 1(2%) hyperthyroid, and 10(20.4%) subclinical hypothyroid. There was a significant relationship between thyroid function and irregular bleeding (P<0.05). Among women, 19(38.8%) had menorrhagia, 16(32.7%) poly menorrhoea, 10(20.5%) intermittent bleeding, and 4(8.1%) oligo menorrhoea. AUB was caused by dysfunctional uterine bleeding in 24(49%), endometrial hyperplasia (with or without atypia) in 9(18.4%), adenomyosis in 6(12.2%), fibroid in 5(10.2%), and ovarian cyst in 1(2%). Thyroid function did not alter abnormal uterine haemorrhage causes.Conclusion: Most women presented with menorrhagia and poly menorrhea between the age 40-45 years with dysfunctional uterine bleeding being the most common cause, and there was strong association between thyroid dysfunction and abnormal uterine bleeding.
Turkey et al. (Sun,) studied this question.