Does the correlation between 18F-FDG PET and DCE-MRI measurements vary with clinical conditions in patients with carotid atherosclerosis?
The moderate correlation between 18F-FDG PET and DCE-MRI in symptomatic carotid plaques suggests a complex interplay between acute inflammation, metabolic activity, and neovascularization.
The correlation between (18)F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI measurements varied with clinical conditions, pointing to a complex interplay between macrophages and neovessels under different pathophysiological conditions. The moderate correlation shown only in symptomatic plaques indicates the presence of acute plaque inflammation with increased metabolic activity and cytokine production by inflammatory cells.
Wang et al. (Fri,) studied this question.
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