The novel ABC classification of intra-device thrombosis accurately predicted peri-device leak following left atrial appendage closure, with Type A indicating sealing and Type C indicating patency.
Observational (n=68)
Blinded investigators for image analysis
No
Does a unifying ABC classification system reproducibly identify sealing and peri-device leak following left atrial appendage closure across different imaging modalities?
A new ABC classification system for assessing sealing after left atrial appendage closure is highly reproducible across imaging modalities and reader experience levels.
p-value: p=<0.001
Type A was associated with sealing irrespective of imaging modality, while Type C was always an indicator of PDL. This unifying classification was highly reproducible across imaging modalities and among readers of differing levels of experience.
Hamadanchi et al. (Mon,) conducted a observational in Non-valvular atrial fibrillation undergoing left atrial appendage closure (n=68). ABC classification of intra-device thrombosis (IDT) was evaluated on Peri-device leak (PDL) in Type A intra-device thrombosis at 90 days by CCT (95% CI 0.7%-14.5%, p=<0.001). The novel ABC classification of intra-device thrombosis accurately predicted peri-device leak following left atrial appendage closure, with Type A indicating sealing and Type C indicating patency.