What question did this study set out to answer?

The study aims to investigate the role of annexin A5 and apelin in placentae from twin pregnancies and their association with adverse outcomes.

April 15, 2026Open Access

Clinicopathological study of placentae of twin pregnancies with emphasis on exploration of expression of two novel markers, annexin a5 and apelin

Key Points

The study aims to investigate the role of annexin A5 and apelin in placentae from twin pregnancies and their association with adverse outcomes.
Examined placentae from twin pregnancies.
Analyzed expression levels of annexin A5 and apelin.
Reduced expression of annexin A5 and apelin was observed in twin pregnancies.
Correlation found between reduced expression and adverse pregnancy outcomes.

Abstract

Both ANXA5 and apelin are vital for placental homeostasis. The reduction in expression of these markers in twin pregnancies indicates their contribution to adverse outcomes of these cases. Studies with larger sample size are required in the future for further exploration of the role of these novel markers.

Clinicopathological study of placentae of twin pregnancies with emphasis on exploration of expression of two novel markers, annexin a5 and apelin

Key Points

Abstract

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