An MRI of a 25-year-old adult male patient after an episode of acute pancreatitis revealed a multiloculated pancreatic head cyst with a mural nodule. Endoscopic biopsy and molecular analysis showed wild-type KRAS, GNAS and TP53. Due to diagnostic uncertainty, a surgical resection was performed and revealed acinar cystic transformation (ACT), a rare benign lesion. ACT should be considered in differential diagnosis of pancreatic cysts, especially in young patients.
Longros et al. (Mon,) studied this question.