June 11, 2013

Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds

Key Points

Key points are not available for this paper at this time.

Abstract

A Pd(II)-catalyzed C-H phosphorylation reaction has been developed using heterocycle-directed ortho-palladation. Both H-phosphonates and diaryl phosphine oxides are suitable coupling partners for this reaction.

Bookmark

Cite This Study

Feng et al. (Tue,) studied this question.

synapsesocial.com/papers/69dff7e72833447a7e255b2e https://doi.org/https://doi.org/10.1021/ja404526x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Annulation of Alkenyl-Substituted Heterocycles via Rhodium-Catalyzed Intramolecular C−H Activated Coupling Reactions2001 · 172 citations
2Chiral P,N-ligands with pyridine-nitrogen and phosphorus donor atoms. Syntheses and applications in asymmetric catalysis2003 · 252 citations
3Discovery of a Series of Phosphonic Acid-Containing Thiazoles and Orally Bioavailable Diamide Prodrugs That Lower Glucose in Diabetic Animals Through Inhibition of Fructose-1,6-Bisphosphatase2010 · 160 citations
4Copper-Catalyzed Synthesis of Unsymmetrical Triarylphosphines2003 · 151 citations
5Catalytic Synthesis of Phosphines and Related Compounds2003 · 107 citations