August 16, 2012Journal of Antimicrobial Chemotherapy89 citationsOpen Access

In vitro evaluation of the potential for resistance development to ceragenin CSA-13

JPJacob Pollard JSJason Snarr VCVed Prakash Chaudhary

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Abstract

CSA-13 retained potent antibacterial activity against S. aureus over the course of 30 serial passages. Resistance generated in Gram-negative bacteria correlates with modifications to the outer membranes of these organisms and was not stable outside of the presence of the antimicrobial.

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synapsesocial.com/papers/69dff881ca6b6a2615860897 https://doi.org/https://doi.org/10.1093/jac/dks276

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