February 12, 2021Open Access

Human Herpesvirus 6 Encephalitis in Immunocompetent and Immunocompromised Hosts

Key Points

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Abstract

The detection of a CSF/blood replication ratio >1 represented a specific feature of immunocompromised patients with HHV-6 encephalitis and could be of special help to establish a diagnosis of HHV-6 encephalitis in hematopoietic stem cell transplant recipients lacking radiologic evidence of limbic involvement.

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Cite This Study

Berzero et al. (Fri,) studied this question.

synapsesocial.com/papers/69dffb92bdd89ea531860ba3 https://doi.org/https://doi.org/10.1212/nxi.0000000000000942

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Human herpes virus 6 infection is a hallmark of cord blood transplant in adults and may participate to delayed engraftment: a comparison with matched unrelated donors as stem cell source2009 · 77 citations
2Human herpesviruses-6 and -7 each cause significant neurological morbidity in Britain and Ireland2005 · 156 citations
3Clinical Outcomes of Human Herpesvirus 6 Reactivation after Hematopoietic Stem Cell Transplantation2005 · 339 citations
4Child and adult forms of human herpesvirus 6 encephalitis2014 · 36 citations
5Human herpesvirus 6 can be detected in cerebrospinal fluid without associated symptoms after allogeneic hematopoietic cell transplantation2014 · 47 citations

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