What question did this study set out to answer?

To evaluate the relationship between matrix metalloproteinase levels and the occurrence of hemorrhagic transformation after ischemic stroke.

April 16, 2026Open Access

Diagnostic Accuracy of MMPs for Predicting Hemorrhagic Transformation After Ischemic Stroke

Key Points

To evaluate the relationship between matrix metalloproteinase levels and the occurrence of hemorrhagic transformation after ischemic stroke.
Assess levels of matrix metalloproteinases in stroke patients
Analyze the occurrence of hemorrhagic transformation
Determine the predictive accuracy of MMP levels for HT events
Identified significant associations between elevated MMP levels and increased risk of hemorrhagic transformation
MMP-9 showed the strongest correlation with HT outcomes
Findings suggest a potential biomarker role for MMPs in stroke management.

Abstract

Ischemic stroke, primarily caused by cerebral artery occlusion, is a leading cause of death and disability. Hemorrhagic transformation (HT) is a known complication that worsens outcomes. Matrix metalloproteinases (MMPs), especially MMP-9, are implicated in neuroinflammation and blood-brain barrier (BBB) disruption after stroke. This study investigates the association between MMP levels and HT events.

Read Full Paperexternally

AI से पूछें

Bookmark

View Full Paper

Cite This Study

Elgenidi et al. (Mon,) studied this question.

synapsesocial.com/papers/69e07c1e2f7e8953b7cbd87b https://doi.org/https://doi.org/10.1212/wn9.0000000000000073

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

AI से पूछें

Bookmark

View Full Paper