What question did this study set out to answer?

To develop a method for detecting systemic lupus erythematosus using surface-enhanced Raman spectroscopy.

April 16, 2026Bulletin of the Russian Academy of Sciences Physics0 citations

Application of Surface-Enhanced Raman Scattering Blood Serum Analysis in the Diagnosis of Systemic Lupus Erythematosus

LBL. A. BratchenkoImmanuel Kant Baltic Federal University YKYu. A. KhristoforovaSamara National Research University ИБИ.А. БратченкоImmanuel Kant Baltic Federal University

Key Points

To develop a method for detecting systemic lupus erythematosus using surface-enhanced Raman spectroscopy.
Utilized surface-enhanced Raman spectroscopy for blood serum analysis.
Applied multivariate analysis to interpret spectral data.
Developed a binary classifier based on projection on latent structure.
Achieved an accuracy of over 95% in identifying systemic lupus erythematosus.
Demonstrated effective differentiation between healthy individuals and patients.

Abstract

We presented an innovative approach to detecting patients with systemic lupus erythematosus based on the combination of surface-enhanced Raman spectroscopy and multivariate analysis. A binary classifier was developed using the projection on the latent structure, allowing for the accurate identification of patients with systemic lupus erythematosus with an accuracy exceeding 95% based on spectral profiles of blood serum.

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Cite This Study

Bratchenko et al. (Sun,) studied this question.

synapsesocial.com/papers/69e07dc72f7e8953b7cbec64 https://doi.org/https://doi.org/10.1134/s1062873825715193

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