Lactobacillus reuteri BNCC186563 Ameliorates Lipid Metabolism Disorder in Obese Mice by Activating the PPARα Signaling Pathway
Key Points
The aim is to investigate the effects of Lactobacillus reuteri BNCC186563 on lipid metabolism disorders in obesity.
Experimental design using obese mouse models
Administration of Lactobacillus reuteri BNCC186563
Assessment of lipid metabolism and PPARα signaling pathway activation
Significant improvement in lipid profiles of treated obese mice
Activation of the PPARα signaling pathway observed after treatment
Reduction in markers of lipid metabolism disorder noted in the intervention group
Abstract
Obesity is a chronic disease that is now recognized as a global epidemic. Therefore, the need for effective therapeutic options to combat obesity cannot be overemphasized. Here, we demonstrate a...