Predictors of benefits and safety events from participation in a lifestyle therapy trial for adults with depression: A secondary analysis of the CALM randomised controlled trial | Synapse
April 17, 2026Open Access
Predictors of benefits and safety events from participation in a lifestyle therapy trial for adults with depression: A secondary analysis of the CALM randomised controlled trial
Key Points
The aim is to identify factors that predict the benefits and safety events associated with lifestyle therapy in adults with depression.
Conducted a secondary analysis of data from the CALM randomised controlled trial.
Included adults diagnosed with depression who participated in lifestyle therapy.
Analyzed predictors of treatment benefits and safety events.
Identified specific lifestyle factors associated with greater benefits from therapy.
Highlighted certain predictors linked to safety events during participation.
Suggested that understanding these predictors can enhance therapeutic interventions.
Abstract
Australian and New Zealand Clinical Trials Registry (https://www.anzctr.org.au/; ACTRN12621000387820).