Temporal trends in diagnostic work-up, treatment, and mortality in locally advanced prostate cancer in 2016–2024: nationwide, population-based study in Sweden

Key Points

• To evaluate the temporal trends in diagnostic processes, treatment approaches, and mortality rates in men with locally advanced prostate cancer from 2016 to 2024.
• Analyzed nationwide, population-based data on men with locally advanced prostate cancer in Sweden.
• Examined trends in the use of MRI before biopsy, radical radiotherapy, and abiraterone treatment.
• Monitored mortality rates over a 3-year period.
• MRI usage before biopsy rose significantly over the analyzed years.
• Radical radiotherapy and abiraterone treatment saw increased application.
• Observed a modest decline in 3-year prostate cancer mortality rates.