What question did this study set out to answer?

The aim is to synthesize (E)-2-(2-benzylidenehydrazinyl)-4-phenylthiazoles using sustainable methods.

April 18, 2026

Sustainable Access to (E)-2-(2-benzylidenehydrazinyl)-4-phenylthiazoles by Ruthenium(II) Catalyst via Dehydrogenative Coupling of Alcohols

SSSaranya SundarBharathidasan University APAnandaraj PennamuthiriyanAnna University, Chennai RRRamesh RenganBharathidasan University

Key Points

The aim is to synthesize (E)-2-(2-benzylidenehydrazinyl)-4-phenylthiazoles using sustainable methods.
Utilized a new ruthenium(II) catalyst in reactions.
Performed acceptorless dehydrogenative coupling of alcohols.
Synthesized and characterized an arene ruthenium(II)-N^O chelating complex.
Successfully derived (E)-2-(2-benzylidenehydrazinyl)-4-phenylthiazoles.
Achieved the synthesis through readily available alcohols.
The catalyst was structurally characterized, confirming its effectiveness.

Abstract

Medicinally important (E) -2- (2-benzylidenehydrazinyl) -4-phenylthiazoles have been derived via acceptorless dehydrogenative coupling (ADC) of readily available alcohols using new ruthenium (II) catalyst. The arene ruthenium (II) -NO chelating complex has been synthesised and structurally characterized. . .

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