Carbamoyl Azide-Drug Conjugates as Supramolecular Gelators: Design, Synthesis, Crystal Structures and Anti-Melanoma Property

Key Points

• The aim is to design and synthesize carbamoyl azide-drug conjugates as effective supramolecular gelators with anti-melanoma properties.
• Employed a crystal engineering approach for synthesizing gelators
• Analyzed structure-property correlations in designed compounds
• Investigated the anti-melanoma properties of the synthesized gelators
• Successfully synthesized novel carbamoyl azide-drug conjugates
• Observations indicate effective supramolecular gel formation
• Demonstrated potential anti-melanoma activity in tests