Biologics including platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs) are increasingly utilized in plastic surgery for applications ranging from facial rejuvenation to wound healing.However, the literature currently contains heterogeneous reporting that undermines evidence synthesis and clinical application.A recent systematic review found that the vast majority of authors failed to disclose final platelet concentrations, concluding that systematic evaluation is limited by high heterogeneity in preparation protocols. 3Orthopedic surgery addressed this problem in 2017 by developing the Minimum Information for Studies Evaluating Biologics in Orthopaedics (MIBO) guidelines through Delphi consensus, establishing
Whitford et al. (Wed,) studied this question.