Identification of a Novel HLA ‐ DPA1 Allele, HLA‐DPA1*02:162 , Using PolyseqOne and Oxford Nanopore Sequencing

Key Points

• To identify a new allele of HLA-DPA1, focusing on its genetic characteristics.
• Utilized PolyseqOne and Oxford Nanopore sequencing techniques.
• Focused on nucleotide sequence analysis around exon 3.
• Identified HLA-DPA1*02:162 differing from HLA-DPA1*02:02:02:01 by a single nucleotide substitution.
• The specific substitution occurs at position 509 (c.509 C>T).