A 4-nitro-3-arylpyrrole Platform for the Divergent Synthesis of Marine Natural Products: Ningalins and Lamellarins

Key Points

• The aim is to develop a scalable method for synthesizing polysubstituted 3-arylpyrroles, important for marine natural products.
• Utilized Barton-Zard reaction for synthesis.
• Focused on polysubstituted 3-arylpyrroles.
• Assessed scalability of the process.
• Successfully synthesized novel 3-arylpyrroles.
• Demonstrated efficiency in the Barton-Zard reaction process.
• Provided a platform for further development of marine natural products.