What question did this study set out to answer?

To evaluate the effectiveness of a gradient-structured PCL membrane for guided bone regeneration.

April 23, 2026Open Access

A novel PCL fiber membrane with a gradient structure for guided bone regeneration

Key Points

To evaluate the effectiveness of a gradient-structured PCL membrane for guided bone regeneration.
Fabricated gradient-structured PCL membrane using humidity/speed-tunable electrospinning
Assessed membrane properties such as delamination prevention and cell infiltration capabilities
The membrane effectively prevents delamination during use
Demonstrated enhanced cell attachment and infiltration
Shows potential as a strategy for improving guided bone regeneration outcomes

Abstract

A gradient-structured PCL membrane was fabricated via humidity/speed-tunable electrospinning. It prevents delamination, guides cell attachment/infiltration, and is a promising strategy for guided bone regeneration.

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