Real-world Impact of Antivascular Endothelial Growth Factor Treatment on Visual and Anatomical Outcomes in Diabetic Macular Edema: A Prospective Observational Study

Key Points

• The study aims to evaluate the effects of anti-VEGF therapy on visual and anatomical parameters in patients with diabetic macular edema.
• Prospective observational study design.
• Assessment of best-corrected visual acuity (BCVA) and central subfield thickness (CST) over 12 months.
• Evaluation of patient characteristics including age, duration of diabetes, and presence of nonproliferative diabetic retinopathy (NPDR).
• Significant improvement in BCVA and CST at 12 months (P < 0.001).
• Younger patients, shorter diabetes duration, and NPDR were correlated with better outcomes.
• Improvements in visual and anatomical parameters were sustained throughout the study duration.