Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy

Key Points

• The aim is to evaluate the effects of brain-responsive neurostimulation in adults with drug-resistant focal epilepsy.
• Participants included adults with refractory focal-onset seizures.
• The intervention involved direct brain-responsive neurostimulation.
• The follow-up duration extended up to 3 years.
• Direct brain-responsive neurostimulation reduced seizure frequency in adults with refractory focal-onset seizures without serious adverse events.
• Class IV evidence supports the intervention's safety over the 3-year follow-up.