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September 14, 2004JAMA1,334 citations

Early Intensive vs a Delayed Conservative Simvastatin Strategy in Patients With Acute Coronary Syndromes

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James A. de Lemos
James A. de LemosGeneral / Preventive / Lipids
MBMichael A. BlazingGeneral / Preventive / Lipids
Stephen D. Wiviott
Stephen D. WiviottGeneral / Preventive / Lipids

Key Points

  • This research aims to assess the impact of early versus delayed statin therapy on cardiovascular outcomes following acute coronary syndromes.
  • Conducted randomized controlled trials comparing early initiation of statin therapy to delayed treatments.
  • Evaluated major cardiovascular events as primary outcomes.
  • Early initiation of statin therapy resulted in a significant reduction in major cardiovascular events compared to delayed treatment.

Abstract

2]3 More recently, 2 ran-domized controlled trials have evaluated earlier initiation of statin therapy following an ACS event and have noted a corresponding early reduction in major cardiovascular events. 5,

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Cite This Study

Lemos et al. (2004) studied this question.

synapsesocial.com/papers/69f7e236b3779c4692288e5ahttps://doi.org/10.1001/jama.292.11.1307
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