Correlation of proteinuria and quantitative anti-dsDNA level in patients of Lupus Nephritis after treatment of pulse cyclophosphamide therapy

Key Points

• This study aims to investigate the relationship between proteinuria levels and anti-dsDNA antibody levels in lupus nephritis patients after cyclophosphamide therapy.
• Patients with lupus nephritis were treated with pulse cyclophosphamide therapy.
• Levels of proteinuria and anti-dsDNA were quantitatively measured post-treatment.
• A significant correlation was found between decreased proteinuria and reduced anti-dsDNA levels after treatment, highlighting the effectiveness of cyclophosphamide.
• Statistical analysis indicated a strong link with p<0.05, suggesting the treatment positively impacts both biomarkers.