Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta‐Analysis | Synapse
May 7, 2026
Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta‐Analysis
Key Points
To assess the impact of maternal overnutrition during pregnancy on the body mass index (BMI) of offspring into early midlife.
Conducted a systematic review and meta-analysis
Evaluated studies linking maternal nutritional status to offspring BMI
Focused on studies measuring BMI gains independent of postpartum BMI (ppBMI).
Offspring of mothers with overnutrition exhibit significantly higher BMI in early midlife, irrespective of ppBMI.
Nutritional interventions during pregnancy are crucial for reducing future obesity risks.
Abstract
higher BMI, independent of ppBMI. These findings underscore the importance of nutritional interventions before and during pregnancy to reduce obesity risk in adulthood.