January 1, 2002

Drugs as P-glycoprotein substrates, inhibitors, and inducers

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Abstract

In humans, there are two P-glycoprotein (P-gp) transporters encoded by MDR1 (PGY1) and MDR3 (also named MDR2 and PGY3) adjacently located at the chromosomal region 7q21 12. The encoded gene pro...

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Cite This Study

Richard B. Kim (Tue,) studied this question.

synapsesocial.com/papers/69ff55fbef8139f8ff775717 https://doi.org/https://doi.org/10.1081/dmr-120001389

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3Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells1993 · 39 citations
4HumanMDR1and Mousemdr1aP-Glycoprotein Alter the Cellular Retention and Disposition of Erythromycin, but Not of Retinoic Acid or Benzo(a)pyrene1998 · 94 citations
5Disposition of Ivermectin and Cyclosporin A in CF-1 Mice Deficient in mdr1a P-Glycoprotein1999 · 125 citations

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