January 1, 2021

Isorhamnetin, the xanthine oxidase inhibitor fromSophora japonica, ameliorates uric acid levels and renal function in hyperuricemic mice

Key Points

Key points are not available for this paper at this time.

Abstract

may reduce the UA levels and alleviate renal injury by inhibiting XOD activity. It potentially functions as a therapeutic drug and dietary supplement to treat hyperuricemia.

Bookmark

Cite This Study

Wang et al. (Fri,) studied this question.

synapsesocial.com/papers/6a02f706bc3ffe278e6539fa https://doi.org/https://doi.org/10.1039/d1fo02719k

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Flavonol tetraglycosides from fruits of Styphnolobium japonicum (Leguminosae) and the authentication of Fructus Sophorae and Flos Sophorae2009 · 89 citations
2The Effects of Ginsenosides and Anserine on the Up-Regulation of Renal Aquaporins 1–4 in Hyperuricemic Mice2019 · 20 citations
3Ethanol Extract of <i>Cudrania tricuspidata</i> Leaf Ameliorates Hyperuricemia in Mice via Inhibition of Hepatic and Serum Xanthine Oxidase Activity2018 · 26 citations
4Hyperuricemia complicated with acute kidney injury is associated with adverse outcomes in patients with severely decompensated acute heart failure2019 · 13 citations
5Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice2017 · 69 citations

Bookmark