Hypertension-susceptibility variants in PLCE1 and ATP2B1 confer a protective effect against anthracycline-related cardiotoxicity in long-term childhood cancer survivors.
Do hypertension-susceptibility variants in PLCE1 and ATP2B1 affect the risk of anthracycline-related cardiotoxicity in long-term childhood cancer survivors?
Hypertension-susceptibility variants in PLCE1 and ATP2B1 may protect against anthracycline-related cardiotoxicity in childhood cancer survivors.
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values in a panel of lymphoblastoid cell lines. Our findings demonstrate that the hypertension-susceptibility variants in PLCE1 and ATP2B1 confer a protective effect on risk of developing anthracycline-related cardiotoxicity, and functional analyses suggest that these genes are influenced by exposure to anthracyclines.
Hildebrandt et al. (Tue,) reported a other. Hypertension-susceptibility variants in PLCE1 and ATP2B1 confer a protective effect against anthracycline-related cardiotoxicity in long-term childhood cancer survivors.