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Synapse
May 15, 1998Blood2,268 citations

Endothelial cells in physiology and in the pathophysiology of vascular disorders.

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DCDouglas B. CinesEPEleanor S. PollakCBClayton A. Buck

Key Points

  • This review aims to explore the role of endothelial cells in both normal physiology and various vascular disorders.
  • Literature review of existing studies on endothelial cell function and pathology.
  • Analysis of endothelial cell roles in maintaining vascular homeostasis and their contribution to disease states.
  • Endothelial cells are crucial for vessel wall permeability and homeostasis.
  • Alterations in endothelial function contribute to a range of vascular disorders, highlighting potential therapeutic targets.

Abstract

THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane that lines the circulatory system with its primary essential function being the maintenance of vessel wall permeability. Shortly after the first description of circulating blood by William Harvey in 1628, the existence of a

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Cite This Study

Cines et al. (1998) studied this question.

synapsesocial.com/papers/6a076895d9167a9c2a585edbhttps://doi.org/10.1182/blood.v91.10.3527
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