Transition Metal-free Chemoselective Synthesis of C3-Styryl Functionalized Di-/tri-substituted Pyrrole Derivatives and Estimation of their Antimicrobial Properties

Key Points

• This research aims to develop an efficient synthesis method for styryl-functionalized pyrrole derivatives and assess their antimicrobial properties.
• Developed a transition-metal-free synthetic route for pyrrole derivatives.
• Employed a chemoselective approach to achieve high efficiency in synthesis.
• Estimated antimicrobial properties using standard assays.
• The newly synthesized pyrrole derivatives exhibit significant antimicrobial activity.
• The method shows higher efficiency compared to traditional synthesis techniques.