Hepatoprotective effects and mechanistic basis of cinnamaldehyde in preclinical liver disease models: A systematic review

Key Points

• The review aims to investigate the hepatoprotective effects of cinnamaldehyde and its mechanisms in liver disease models.
• Systematic review of preclinical studies evaluating cinnamaldehyde's effects on liver disease models.
• Data extracted from registered protocols and various studies in the field.
• Cinnamaldehyde exhibited significant hepatoprotective properties across various liver disease models.
• Mechanistic pathways involving antioxidant and anti-inflammatory effects were highlighted.