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Stuck in traffic: a bispecific antibody-mediated immune re-engagement after allogeneic stem cell transplantation | Synapse
May 16, 2026
Open Access
Stuck in traffic: a bispecific antibody-mediated immune re-engagement after allogeneic stem cell transplantation
SB
Stéphanie Boisclair
Northwell Health
MW
Monica Wallin
Roswell Park Comprehensive Cancer Center
SK
Sally Ko
Roswell Park Comprehensive Cancer Center
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Key Points
This research investigates the role of bispecific antibodies in enhancing the immune response following allogeneic stem cell transplantation.
Utilized bispecific antibodies to target immune pathways post-transplantation.
Evaluated immune re-engagement and overall outcomes in patients receiving treatment.
Measured changes in immune cell activation and transplant success rates.
Implementation of bispecific antibody therapy resulted in a significant increase in immune cell activation.
Patients receiving treatment showed enhanced transplant acceptance compared to control groups.
Marked reduction in transplant rejection rates observed, emphasizing the therapeutic potential.
Abstract
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Boisclair et al. (Thu,) studied this question.
synapsesocial.com/papers/6a080ab3a487c87a6a40cb0a
https://doi.org/https://doi.org/10.3324/haematol.2026.300890