CSF3R-mutated chronic neutrophilic leukemia: a two-center study of 44 consecutive patients

Key Points

• Investigate the clinical and genetic characteristics of CSF3R-mutated chronic neutrophilic leukemia.
• Conducted in two centers with a sample size of 44 consecutive patients diagnosed with chronic neutrophilic leukemia.
• Analyzed genetic mutations specifically focusing on CSF3R and their clinical implications.
• Identified specific CSF3R mutations in all patients, contributing to the understanding of chronic neutrophilic leukemia.
• Reported various clinical manifestations associated with these mutations, indicating diverse patient outcomes.