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pines, which raise seizure thresholds and reduce seizure durations; the use of minimal currents with unknown consequences to seizure pattern and duration; and the failure to monitor seizures, both to describe the electro- graphic durations and patterns and to assure us that an effective fit did, indeed, occur.The last factor is particularly important.In their survey of British practice, Pippard and Ellam15 found that even sophisticated observers could misjudge seizure duration and decide that a short fit was "effective," when it was not.The controversy about seizures and currents will continue until seizure durations and seizure patterns are monitored objectively and researchers determine the parameters of the fit that have the highest correlation with anti- depressant efficacy.A change of focus is needed-from the electric current (and, in the United States, the electrode location) to the biochemical, neurohumoral, and electro- graphic factors in the fit which accompany and which facilitate clinical change.
Verdier-Taillefer et al. (Sat,) studied this question.
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