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September 1, 1998Baillière s Clinical Obstetrics and Gynaecology3 citationsOpen Access

9 The effects of epidural analgesia on the course and outcome of labour

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MFMieczyslaw FinsterASAlan C. Santos

Key Result

Epidural blocks provide superior pain relief over systemically administered opioids during labour, though their effect on labour progress and operative delivery rates remains controversial.

Structured PICO

Does epidural analgesia affect the course and outcome of labour compared to systemically administered opioids?

P
Population
Women in labour
I
Intervention
Epidural analgesia
C
Comparator
Systemically administered opioids
O
Outcome
Course and outcome of labour (length of labour, incidence of instrumental or operative delivery) and pain relief

While epidural analgesia provides superior pain relief during labor compared to systemic opioids, its impact on labor progression and operative delivery rates remains unclear due to study limitations.

Limitations

  • Existing prospective randomized studies are contradictory and unreliable due to small patient populations and high cross-over rates
  • Existing prospective randomized studies are contradictory and not very reliable owing to small patient populations and high cross-over rates
  • Retrospective and non-randomized studies cannot rule out selection bias

Abstract

The potential effects of epidural analgesia on the progress and outcome of labour have been the subject of lasting controversy. Retrospective reviews indicate that epidurals are associated with longer labours and/or an increase in the incidence of instrumental or operative delivery. Similar results were obtained in non-randomized prospective studies. None of them established a causal relationship, because without randomization the selection bias cannot be ruled out. Other factors, such as premature rupture of membranes and maternal socioeconomic status, may affect the outcome of labour. It was also reported that introduction of the on-demand epidural service did not increase the primary caesarean section rate. The few prospective randomized studies are contradictory and not very reliable owing to small patient populations and high cross-over rates. There is, however, unanimity among the authors regarding the superiority of pain relief provided by epidural blocks over systemically administered opioids.

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Cite This Study

Finster et al. (1998) conducted a review in Labour. Epidural analgesia vs. Systemically administered opioids was evaluated on Pain relief and progress/outcome of labour. Epidural blocks provide superior pain relief over systemically administered opioids during labour, though their effect on labour progress and operative delivery rates remains controversial.

synapsesocial.com/papers/6a095bdb4db7968590512ff5https://doi.org/10.1016/s0950-3552(98)80079-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of epidural analgesia on the progress of labor and the mode of delivery1995 · 2 citations
  2. 2Labor analgesia: An update on the effect of epidural analgesia on labor outcome2013 · 5 citations
  3. 3The Impact of Epidural Analgesia on the Dynamics of Labor and Perinatal Outcomes in Nulliparous Women: A Prospective Cohort Study2025 · 4 citations
  4. 4The Effect of Epidural Analgesia on Maternal and Neonatal Birth Outcomes: A Retrospective Analysis of 129 Cases2026
  5. 5The effects of epidural analgesia in normal labour2018