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July 1, 1974Cancer72 citations

Prostate carcinoma: Radiation treatment of the primary and regional lymphatics

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DHDennis R. HillQCQuintous E. CrewsPWPatrick C. Walsh

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Abstract

We reviewed the records of 68 consecutive patients with localized or locally advanced prostate carcinoma treated with definitive radiation from 1959 through 1970. In patients followed over 5 years, the lymphatics within the true pelvis received at least 5000 rads in 5 to 6 1/2 weeks, and the primary received 6000 to 7500 rads in 7 to 11 weeks. There were 64% 5-year and 38% 10-year actuarial survivals, and clinical local control in 91% of the 5- to 12-year survivors (21/23). Additionally, negative prostate biopsies were obtained in 76% of the patients sampled more than 1-year after treatment (16/21). This report offers further evidence that carcinoma of the prostate, even if inoperable, is curable with radiation, but we could not demonstrate an improvement in 5-year survival, 10-year survival, or disease-free rate with pelvic nodal treatment.

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Hill et al. (1974) studied this question.

synapsesocial.com/papers/6a0d6ec1c9ce454950a4d236https://doi.org/10.1002/1097-0142(197407)34:1<156::aid-cncr2820340123>3.0.co;2-q
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