Functional mitral regurgitation is an increasingly prevalent condition, affecting 2.0-2.5 million people in the USA in 2000, with 1-year mortality rates of 15-40% after developing heart failure.
This contemporary review outlines the increasing prevalence of functional mitral regurgitation and summarizes current diagnostic and therapeutic strategies.
non ischemic etiologies. The prevalence of FMR is increasing, as 2.0-2.5 million people in the USA were diagnosed with FMR in 2000-and this number is expected to double to 4 million by 2030. FMR tends to develop in a significant number of patients after myocardial infarction (MI) and many develop heart failure (HF) subsequently with mortality rates ranging from 15-40% at 1 year. Therefore, there has been much interest and effort to develop optimized methods for quantifying and classifying the severity of FMR, as well as developing effective therapeutic interventions to improve outcomes in patients with significant FMR. Echocardiogram is typically the primary diagnostic method of assessment, however, there have been various technological advances including cardiac CT and cardiac MRI that can better guide quantification and management of this disease. Management of this disease is mostly aimed at optimizing left ventricular (LV) remodeling with surgical and transcatheter management gaining more popularity with recent times. The purpose of this paper is to provide a comprehensive review of the current evaluation methods and interventional strategies for FMR.
Vajapey et al. (Tue,) conducted a review in Functional mitral regurgitation. Functional mitral regurgitation is an increasingly prevalent condition, affecting 2.0-2.5 million people in the USA in 2000, with 1-year mortality rates of 15-40% after developing heart failure.