An education and support programme for GPs significantly increased the percent of time within 0.5 INR from target from 49.5% at baseline to 60%, with no difference among specific intervention models.
RCT
Stratified randomization
Yes
Does providing education, feedback, point-of-care INR testing, or computer-assisted advice improve the time in target INR range for patients on oral anticoagulation managed by general practitioners?
An education and support program for general practitioners significantly improves the quality of oral anticoagulation management, though specific additions like point-of-care testing or computer-assisted advice did not provide further incremental benefit.
Absolute Event Rate: 60% vs 49.5%
AIMS: In Belgium, general practitioners (GPs) mainly manage oral anticoagulation therapy. To improve the quality of oral anticoagulation management by GPs and to compare different models and interventions, a randomized clinical trial was performed. METHODS AND RESULTS: Stratified randomization divided 66 GP-practices into four groups. A 6-month retrospective analysis assessed the baseline quality. In the prospective study, each group received education on oral anticoagulation, anticoagulation files, and patient information booklets (groups A, B, C, and D). Group B additionally received feedback every 2 months on their anticoagulation performance; group C determined the international normalized ratio (INR) with a CoaguChek device in the doctor's office or at the patient's home; and group D received Dawn AC computer assisted advice for adapting oral anticoagulation. For the different groups, the time spent in target INR range (Rosendaal's method) and adverse events related to anticoagulation were determined and compared with the same quality indicators at baseline. There was a significant increase in per cent of time within 0.5 INR from target, from 49.5% at baseline to 60% after implementing the different interventions. However, neither the per cent in target range nor the event rates differed among the four groups. CONCLUSION: The interventions significantly improved the quality of management of oral anticoagulation by Belgian GPs, mainly as a result of an education and support programme.
Claes et al. (Wed,) conducted a rct in Oral anticoagulation therapy. Education, anticoagulation files, and patient information booklets (with optional feedback, CoaguChek, or computer advice) vs. Baseline management (retrospective) was evaluated on Time spent in target INR range (Rosendaal's method) and adverse events. An education and support programme for GPs significantly increased the percent of time within 0.5 INR from target from 49.5% at baseline to 60%, with no difference among specific intervention models.