What does this research mean for the field?

Q: What does this research mean for the field?

Mindfulness-based interventions significantly reduce symptoms of anxiety, depression, and stress in patients with coronary artery disease. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 31, 2024Open Access

Effect of mindfulness-based interventions on anxiety, depression, and stress in patients with coronary artery disease: a systematic review and meta-analysis of randomized controlled trials

Structured PICO

Do mindfulness-based interventions improve anxiety, depression, and stress in patients with coronary artery disease?

Population

623 adult participants diagnosed with coronary artery disease (CAD) pooled from 8 RCTs, mean age 56.96 ± 4.89, 72.2% male.

Intervention

Mindfulness-based interventions (MBIs), primarily mindfulness-based stress reduction (MBSR) and mindfulness-based art therapy (MBAT), with varying dosages and durations (5 days to 1 year).

Comparator

Active or inactive control groups (including waitlist, conventional nursing care, early cardiac rehabilitation, written advice, routine care, or self-help booklet).

Outcome

Mental health status in regards to anxiety, depression, and stress measured by psychometric scales (e.g., HADS, BDI, PSS).patient reported

Mindfulness-based interventions provide a statistically significant beneficial effect on anxiety, depression, and stress in patients with coronary artery disease.

Abstract

Background Adopting lifestyle interventions is pivotal in coronary artery disease (CAD) management and prevention to amplify cardiovascular and mental well-being. This study aims to quantify the effect of mindfulness-based interventions (MBIs) on anxiety, depression and stress in CAD patients. Methods A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted by searching four electronic databases (PubMed, CENTRAL, Scopus, and Science Direct) through December 2023. The risk of bias was assessed using the PEDro tool, and the study outcomes were expressed as standard mean difference at 95% CI. Results Out of 1838 yielded results, eight RCTs involving 623 participants with a mean age of 56.96 ± 4.89 met the prespecified eligibility criteria. The pooled results showed a statistically significant and beneficial effect of MBIs on CAD patients’ mental health status in regards to anxiety (SMD = −0.83; 95% CI −1.19, −0.46, p 0.001), depression (SMD = − 0.86; 95% CI −1.14, −0.58, p 0.001), and stress (SMD = −0.69; 95% CI −1.27, −0.12, p = 0.02). The subgroup sensitivity analyses based on the region (Asia vs. Europe) indicated a statistically non-significant subgroup effect of MBIs on anxiety ( I 2 = 63.9%, p = 0.10) and depression ( I 2 = 25.8%, p = 0.25), and a significant effect on stress ( I 2 = 80.0%, p = 0.03). Although the methodological quality of the trials was generally satisfactory, all studies lacked allocation concealment and blinding. Additionally, gender imbalances, and inadequate follow-up may have potentially compromised the validity of the trials. Conclusion Mindfulness-based interventions are beneficial for improving CAD patients’ anxiety, depression and stress symptoms. Nevertheless, it is imperative to conduct more rigorous and robust studies with an equal gender ratio and long-term follow-up.

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Cite This Study

Manan et al. (Wed,) studied this question.

synapsesocial.com/papers/6a1093932badbc352a004b4e https://doi.org/https://doi.org/10.3389/fpsyg.2024.1435243

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