Key points are not available for this paper at this time.
To Editor:— The problem of hemorrhage caused by bishydroxycoumarin (dicumarol®) which was discussed editorially inThe JournalDec. 23, 1950 (page 1466) deserves serious consideration. It involves more than the vagaries of Quick test of prothrombin time. If this test is carried out as I described inThe Journal( 110 :1658 May 14 1938), with correction of a typographical error ( 111 :1775, Nov. 5 1938), it will be found that vagaries are conspicuously absent. Much of trouble can be attributed to indiscriminate flood of modifications of original test and to reckless introductions of various types of thromboplastin. The thromboplastic reagent that I developed was result of years of meticulous study and testing. In spite of its commercial possibilities, it was made available without patent attachments. It was described so explicitly that any technician who is capable of following cook book directions
Armand J. Quick (Sat,) studied this question.