This case report provides evidence supporting the role of excessive sympathetic nervous system activation in the pathogenesis of neurogenic stunned myocardium, extending its association to peripheral neuropathy like Guillain-Barre syndrome.
Neurogenic stunned myocardium (NSM), a syndrome of reversible left ventricular dysfunction best described after subarachnoid hemorrhage, has not been associated with peripheral neuropathy. We describe a woman with Guillain-Barre syndrome in whom a syndrome compatible with NSM developed in the setting of a physiologically documented increase in sympathetic cardiovascular tone. This case supports the presumed unifying role of excessive sympathetic nervous system activation in the pathogenesis of NSM.
Bernstein et al. (Tue,) studied this question.
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