Isolated ventricular non-compaction in adults is an increasingly recognized genetic cardiac disease with a poor prognosis in those with impaired systolic function, though it is often underdiagnosed.
Isolated ventricular non-compaction is an increasingly recognized genetic cardiomyopathy with a poor prognosis when associated with impaired systolic function, highlighting the need for improved diagnostic awareness.
Isolated ventricular non-compaction (IVNC) in adults is a genetic cardiac disease of emerging importance with a distinct clinical and pathophysiological presentation. The body of evidence for the underlying genetic basis of the disease has also grown. Prognosis remains poor for patients with impaired systolic left ventricular function, as treatment options are very limited. The diagnosis of IVNC, however, is often missed, most often as a consequence of ignorance of the condition. The relevant clinical issues and the emerging concepts of the aetiology of IVNC are summarised.
Jenni et al. (Tue,) conducted a review in Isolated ventricular non-compaction (IVNC). Isolated ventricular non-compaction in adults is an increasingly recognized genetic cardiac disease with a poor prognosis in those with impaired systolic function, though it is often underdiagnosed.