Patients with pulmonary arterial hypertension had significantly higher right ventricular kinetic energy work density (94.7 vs 61.7 mJ/mL) and percent pulmonary artery energy loss compared to healthy subjects.
Observational (n=19)
No
Does 4D flow MRI identify altered right ventricular kinetic energy work density and viscous energy dissipation in patients with pulmonary arterial hypertension compared to healthy subjects?
4D flow MRI reveals significantly increased right ventricular kinetic energy work density and pulmonary artery viscous energy loss in PAH patients, offering potential novel imaging markers for RV function.
Absolute Event Rate: 94.7% vs 61.7%
p-value: p=0.007
The data contains human subject information that is limited to a small patient population in a single institution. On the IRB form, it clearly states that the data obtained from the patients will be stored on secure computers within the hospital of the University of Pennsylvania. Data are available upon request from the University of Pennsylvania Institutional Ethics Committee for researchers who meet the criteria for access to confidential data.
Han et al. (2015) conducted an observational in Pulmonary Arterial Hypertension (n=19). 4D Flow MRI vs. Healthy subjects was evaluated on Right ventricular kinetic energy work density (p=0.007). Patients with pulmonary arterial hypertension had significantly higher right ventricular kinetic energy work density (94.7 vs 61.7 mJ/mL) and percent pulmonary artery energy loss compared to healthy subjects.